Sodium/glucose cotransporter 1, ELISA Kit

Sodium/glucose cotransporter 1; Na(+)/glucose cotransporter 1; High affinity sodium-glucose cotransporter; Solute carrier family 5 member 1; SLC5A1; NAGT; SGLT1

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of SLC5A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2886392 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Sodium/glucose cotransporter 1 (SLC5A1) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SLC5A1. The ELISA analytical biochemical technique of the MBS2886392 kit is based on SLC5A1 antibody-SLC5A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SLC5A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SLC5A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

60,097 Da

solute carrier family 5 (sodium/glucose cotransporter), member 1

sodium/glucose cotransporter 1

Sodium/glucose cotransporter 1

NAGT; SGLT1; Na(+)/glucose cotransporter 1  [Similar Products]

SC5A1_HUMAN

This gene encodes a member of the sodium-dependent glucose transporter (SGLT) family. The encoded integral membrane protein is the primary mediator of dietary glucose and galactose uptake from the intestinal lumen. Mutations in this gene have been associated with glucose-galactose malabsorption. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

SLC5A1: Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. Expressed mainly in intestine and kidney. Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.

Protein type: Transporter, SLC family; Transporter; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 22q12.3

Cellular Component: apical plasma membrane; brush border membrane; integral to plasma membrane; intercellular junction; plasma membrane

Molecular Function: glucose:sodium symporter activity; protein binding

Biological Process: carbohydrate metabolic process; glucose transport; hexose transport; intestinal absorption; metanephros development; sodium ion transport; transmembrane transport

Disease: Glucose/galactose Malabsorption

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