Full Product Name
ABCB6 Antibody
Product Gene Name
anti-ABCB6 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9NP58
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein A column containing 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.
Other Notes
Small volumes of anti-ABCB6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCB6 antibody
Rabbit polyclonal ABCB6 (1) antibody was raised against a recombinate human ABCB6 protein 598-818aa (BC000559).
Product Categories/Family for anti-ABCB6 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-ABCB6 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ABCB6 antibody
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-500
Testing Data of anti-ABCB6 antibody
Testing Data of anti-ABCB6 antibody
NCBI/Uniprot data below describe general gene information for ABCB6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005680.1
[Other Products]
NCBI GenBank Nucleotide #
NM_005689.3
[Other Products]
UniProt Primary Accession #
Q9NP58
[Other Products]
UniProt Secondary Accession #
O75542; Q49A66; Q59GQ5; Q6ZME6; Q96ME8; Q9HAQ6; Q9HAQ7[Other Products]
UniProt Related Accession #
Q9NP58[Other Products]
Molecular Weight
88,600 Da
NCBI Official Full Name
ATP-binding cassette sub-family B member 6, mitochondrial isoform 1
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 6 (Langereis blood group)
NCBI Official Symbol
ABCB6 [Similar Products]
NCBI Official Synonym Symbols
ABC; LAN; PRP; umat; MTABC3
[Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 6, mitochondrial
UniProt Protein Name
ATP-binding cassette sub-family B member 6, mitochondrial
UniProt Synonym Protein Names
Mitochondrial ABC transporter 3; Mt-ABC transporter 3; P-glycoprotein-related protein; Ubiquitously-expressed mammalian ABC half transporter
Protein Family
ABC transporter B family
UniProt Gene Name
ABCB6 [Similar Products]
UniProt Synonym Gene Names
MTABC3; PRP; UMAT; Mt-ABC transporter 3 [Similar Products]
NCBI Summary for ABCB6
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. This protein is a member of the heavy metal importer subfamily and plays a role in porphyrin transport. This gene is the molecular basis of the Langereis (Lan) blood group antigen and mutations in this gene underlie familial pseudohyperkalemia and dyschromatosis universalis hereditaria. [provided by RefSeq, Mar 2017]
UniProt Comments for ABCB6
Binds heme and porphyrins and functions in their ATP-dependent uptake into the mitochondria. Plays a crucial role in heme synthesis.
Product References and Citations for anti-ABCB6 antibody
(1) Saito, A., Kawamoto, M. and Kamatani, N. Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. J. Hum. Genet. 54 (6), 317-323 (2009).
Research Articles on ABCB6
1. ABCB6 missense mutations in red blood cells from subjects with familial pseudohyperkalemia show elevated potassium ion efflux.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
