Full Product Name
MRAS Antibody
Product Synonym Names
Ras-related protein M-Ras; Ras-related protein R-Ras3; MRAS; RRAS3
Product Gene Name
anti-MRAS antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O14807
Species Reactivity
Human, Mouse
Purity/Purification
Antigen Affinity Purified
Immunogen
Recombinant human Ras-related protein M-Ras protein (C-130AA)
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-12532 / sc-8168
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-MRAS antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-MRAS antibody
May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway.
Applications Tested/Suitable for anti-MRAS antibody
ELISA (EIA), Western Blot (WB)
Western Blot (WB) of anti-MRAS antibody
Western blot
All lanes: MRAS antibody at 3.44 ug/ml
Lane 1: Mouse brain tissue
Lane 2: Mouse heart tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 24,16 kDa
Observed band size: 24,32 kDa
NCBI/Uniprot data below describe general gene information for MRAS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001078518.1
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NCBI GenBank Nucleotide #
NM_001085049.2
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UniProt Primary Accession #
O14807
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UniProt Secondary Accession #
Q86WX8; B4DIK0[Other Products]
UniProt Related Accession #
O14807[Other Products]
Molecular Weight
15,542 Da
NCBI Official Full Name
ras-related protein M-Ras isoform 1
NCBI Official Synonym Full Names
muscle RAS oncogene homolog
NCBI Official Symbol
MRAS [Similar Products]
NCBI Official Synonym Symbols
M-RAs; RRAS3; R-RAS3
[Similar Products]
NCBI Protein Information
ras-related protein M-Ras
UniProt Protein Name
Ras-related protein M-Ras
UniProt Synonym Protein Names
Ras-related protein R-Ras3
Protein Family
Ras-related protein
UniProt Gene Name
MRAS [Similar Products]
UniProt Synonym Gene Names
RRAS3 [Similar Products]
UniProt Entry Name
RASM_HUMAN
NCBI Summary for MRAS
This gene encodes a member of the Ras family of small GTPases. These membrane-associated proteins function as signal transducers in multiple processes including cell growth and differentiation, and dysregulation of Ras signaling has been associated with many types of cancer. The encoded protein may play a role in the tumor necrosis factor-alpha and MAP kinase signaling pathways. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
UniProt Comments for MRAS
MRas: May serve as an important signal transducer for a novel upstream stimuli in controlling cell proliferation. Weakly activates the MAP kinase pathway. Belongs to the small GTPase superfamily. Ras family.
Protein type: G protein; Oncoprotein; G protein, monomeric, Ras; G protein, monomeric
Chromosomal Location of Human Ortholog: 3q22.3
Molecular Function: GTP-dependent protein binding; GTPase activity; protein binding
Biological Process: actin cytoskeleton organization and biogenesis; multicellular organismal development; muscle development; Ras protein signal transduction
Research Articles on MRAS
1. The association of the MARS rs6782181 polymorphism and serum lipid levels is different between the Mulao and Han populations, or between males and females in the both ethnic groups.
Precautions
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Disclaimer
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