Product Name
Nuclear factor erythroid 2-related factor 3 (Nfe2l3), Recombinant Protein
Full Product Name
Recombinant Mouse Nuclear factor erythroid 2-related factor 3 (Nfe2l3)
Product Gene Name
Nfe2l3 recombinant protein
[Similar Products]
Product Synonym Gene Name
Nfe2l3[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-660aa, full length protein
Sequence
MKLPKPWWAG GGLLQLTILL SLVGLRVDLD LFLPPPAAAL WEELLPLCPT RPASASNPFS ASEGWERTPL LPAKGRLLHE VRALGVPFIP RTRVDAWLVH SVATGNADGA HGLLGTAASS AVGDGGQSAS AGGGDPRAAH SSPLAAEEEE EKAAEPTAQV PDAGGCGSQE NGMLREKSEA VDHSSQQEEN EEGVSAQAKS RQQSKTEEHK MACASAREAE KITEARNESH LHWSDTSFSL EDLFQLLSSQ PEHSLEGISV EDIPPFLSSV CESVNSSAQN INLSQAISHD VNLHEAMLLY PNNTFRRDPS ARSSQAQEPF LQLNPHTNPE QATPAMSLPP FDNQMRNLTS QDLLYDLDSN IFDGINLMSL ATGFSPLEVS QLFEEPDSGL SLNSSYNSTS LTNSYRIYDG TVGYNSDLQS LCHDLGAVGG CYPEPHKHCH MDHRTIAGFH VSLECQQVFH DHTYHLQSGA SEPTSESFAW SEKSQKTSGC LDNPDRNLSR DEQRAKALHI PFSVDEIVRM PVDSFNSMLS RYYLTDLQVS LIRDIRRRGK NKVAAQNCRK RKLDIILNLE DDICNLQAKK EALKNEQTQC SKAIDIMRQK LHGLHQDVFN RLRDDQGRPV NPSQYALQYS HDGTVLIVPK ELISSGHKKE APKGKRERRN
3D Structure
ModBase 3D Structure for Q9WTM4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Nfe2l3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Nfe2l3 recombinant protein
This gene encodes a member of the cap n collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18.
NCBI/Uniprot data below describe general gene information for Nfe2l3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_035033.1
[Other Products]
NCBI GenBank Nucleotide #
NM_010903.2
[Other Products]
UniProt Primary Accession #
Q9WTM4
[Other Products]
UniProt Related Accession #
Q9WTM4[Other Products]
Molecular Weight
72,707 Da
NCBI Official Full Name
nuclear factor erythroid 2-related factor 3
NCBI Official Synonym Full Names
nuclear factor, erythroid derived 2, like 3
NCBI Official Symbol
Nfe2l3 [Similar Products]
NCBI Official Synonym Symbols
Nrf3
[Similar Products]
NCBI Protein Information
nuclear factor erythroid 2-related factor 3
UniProt Protein Name
Nuclear factor erythroid 2-related factor 3
UniProt Synonym Protein Names
Nuclear factor, erythroid derived 2, like 3
Protein Family
Nuclear factor erythroid 2-related factor
UniProt Gene Name
Nfe2l3 [Similar Products]
UniProt Synonym Gene Names
Nrf3; NF-E2-related factor 3; NFE2-related factor 3 [Similar Products]
UniProt Comments for Nfe2l3
Activates erythroid-specific, globin gene expression.
Research Articles on Nfe2l3
1. Pla2g7 plays a crucial physiological role in smooth muscle cell differentiation from stem cells, and interactions between Nrf3 and Pla2g7 are essential.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.