Product Name
CIR (CIR1), Polyclonal Antibody
Full Product Name
CIR antibody - C-terminal region
Product Gene Name
anti-CIR1 antibody
[Similar Products]
Product Synonym Gene Name
CIR[Similar Products]
Antibody/Peptide Pairs
CIR peptide (MBS3229092) is used for blocking the activity of CIR antibody (MBS3204125)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
Synthetic peptide located within the following region: RSRSPGSYKQ RETRKRAQRN PGEEQSRRND SRSHGTDLYR GEKMYREHPG
3D Structure
ModBase 3D Structure for Q86X95
Purity/Purification
Affinity Purified
Form/Format
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human CIR
Preparation and Storage
For short term use, store at 2-8 degree C up to 1 week. For long term storage, store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Other Notes
Small volumes of anti-CIR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CIR1 antibody
This is a rabbit polyclonal antibody against CIR. It was validated on Western Blot using a cell lysate as a positive control.
Target Description: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Product Categories/Family for anti-CIR1 antibody
Polyclonal; Transcription Factor; Transcription Regulation; Transcription Regulation; Chromatin & Nuclear Signaling; Epigenetics; Transcription Factors;
Applications Tested/Suitable for anti-CIR1 antibody
Western Blot (WB)
Western Blot (WB) of anti-CIR1 antibody
WB Suggested Anti-CIR Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Transfected 293T
NCBI/Uniprot data below describe general gene information for CIR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_004873
[Other Products]
NCBI GenBank Nucleotide #
NM_004882
[Other Products]
UniProt Primary Accession #
Q86X95
[Other Products]
UniProt Related Accession #
Q86X95[Other Products]
NCBI Official Full Name
corepressor interacting with RBPJ 1
NCBI Official Synonym Full Names
corepressor interacting with RBPJ, 1
NCBI Official Symbol
CIR1 [Similar Products]
NCBI Official Synonym Symbols
CIR
[Similar Products]
NCBI Protein Information
corepressor interacting with RBPJ 1
UniProt Protein Name
Corepressor interacting with RBPJ 1
UniProt Synonym Protein Names
CBF1-interacting corepressor; Recepin
UniProt Gene Name
CIR1 [Similar Products]
UniProt Synonym Gene Names
CIR [Similar Products]
UniProt Entry Name
CIR1_HUMAN
Research Articles on CIR1
1. C, ribonucleotide reductase M1 (RRM1) rs1465952T>C and solute carrier family 38, member 4 (SLC38A4) rs2429467C>T), may play a role in the pathogenesis of lung cancer">three SNPs (corepressor interacting with RBPJ 1 (CIR1) rs13009079T>C, ribonucleotide reductase M1 (RRM1) rs1465952T>C and solute carrier family 38, member 4 (SLC38A4) rs2429467C>T), may play a role in the pathogenesis of lung cancer
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
