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EIF1A, X-Chromosomal/EIF1AX, Recombinant Protein

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产品名称: EIF1A, X-Chromosomal/EIF1AX, Recombinant Protein
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简单介绍

EIF1A, X-Chromosomal/EIF1AX, Recombinant Protein


EIF1A, X-Chromosomal/EIF1AX, Recombinant Protein  的详细介绍
Product Name

EIF1A, X-Chromosomal/EIF1AX, Recombinant Protein

Full Product Name

Recombinant Human EIF1A, X-Chromosomal/EIF1AX Protein (N-6His)

Product Synonym Names
Eukaryotic Translation Initiation Factor 1A X-Chromosomal; eIF-1A X Isoform; Eukaryotic Translation Initiation Factor 4C; eIF-4C; EIF1AX; EIF1A; EIF4C
Product Gene Name

EIF1AX recombinant protein

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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Sequence Positions
Met1-Ile144
3D Structure
ModBase 3D Structure for P47813
Host
E Coli
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Species
Human
Endotoxin
<1.0 EU per ug as determined by LAL test.
Fusion Tag
N-6His
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of EIF1AX recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
EIF1AX recombinant protein
Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
NCBI/Uniprot data below describe general gene information for EIF1AX. It may not necessarily be applicable to this product.
NCBI GI #
4503499
NCBI GeneID
1964
NCBI Accession #
NP_001403.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001412.3 [Other Products]
UniProt Primary Accession #
P47813 [Other Products]
UniProt Secondary Accession #
Q0VGC2; Q5JPS5; Q5JPS6; B2R5U5[Other Products]
UniProt Related Accession #
P47813[Other Products]
Molecular Weight
Molecular Mass: 18.6 kDa
Actual Protein Molecular Mass: 22 kDa
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NCBI Official Full Name
eukaryotic translation initiation factor 1A, X-chromosomal
NCBI Official Synonym Full Names
eukaryotic translation initiation factor 1A X-linked
NCBI Official Symbol
EIF1AX  [Similar Products]
NCBI Official Synonym Symbols
EIF1A; EIF4C; eIF-1A; eIF-4C; EIF1AP1
  [Similar Products]
NCBI Protein Information
eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Protein Name
Eukaryotic translation initiation factor 1A, X-chromosomal
UniProt Synonym Protein Names
Eukaryotic translation initiation factor 4C; eIF-4C
Protein Family
Eukaryotic translation initiation factor
UniProt Gene Name
EIF1AX  [Similar Products]
UniProt Synonym Gene Names
EIF1A; EIF4C; eIF-1A X isoform; eIF-4C  [Similar Products]
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NCBI Summary for EIF1AX
This gene encodes an essential eukaryotic translation initiation factor. The protein is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA. [provided by RefSeq, Jul 2008]
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UniProt Comments for EIF1AX
Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
Research Articles on EIF1AX
1. Study identified a new RNA-induced silencing complex component, eIF1A, which directly interacts with the MID-domain of Ago2 and functions in DICER-independent miRNA biogenesis and miRNA-mediated RNA interference.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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